Synthesis of novel photochromic pyrans via palladium-mediated reactions

نویسندگان

  • Christoph Böttcher
  • Gehad Zeyat
  • Saleh A Ahmed
  • Elisabeth Irran
  • Thorben Cordes
  • Cord Elsner
  • Wolfgang Zinth
  • Karola Rueck-Braun
چکیده

Photochromic pyrans for applications in material and life sciences were synthesized via palladium-mediated cyanation, carbonylation and Sonogashira cross-coupling starting from bromo-substituted naphthopyran 1 and benzopyrans 2a/b. A novel photoswitchable benzopyran-based omega-amino acid 6 for Fmoc-based solid-phase peptide synthesis is presented. The photochromic behaviour of the 3-cyano-substituted benzopyran 5a was investigated by time-resolved absorption spectroscopy in the picosecond time domain.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2009